According to a statement by Senior Special Assistant to the President on Media and Publicity, Office of the Vice President, Mr Laolu Akande, Osinbajo will join other leaders across Africa and beyond to grace the event scheduled to hold at the Samuel K. Doe Stadium in Monrovia.
The Vice President will also attend other events later in the day in Monrovia as part of the Liberian national celebration.
Liberia was founded in 1822 when freed black people started relocating to West Africa from the United States.
On July 26, 1847, the country proclaimed its independence and became the Republic of Liberia.
Osinbajo, who will be accompanied on the trip by Minister of State Foreign Affairs Ambassador Zubairu Dada; and Special Adviser to the President on Economic Matters, Dr. (Amb.) Adeyemi Dipeolu; is expected back on Tuesday